Publication details

Co je nového v srdečním selhání se zachovalou ejekční frakcí levé komory za posledních pět let?

Title in English What is new in heart failure with preserved ejection fraction within last five years?
Authors

GREGOROVÁ Zdeňka MELUZÍN Jaroslav ŠPINAROVÁ Lenka

Year of publication 2014
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Citation
Web http://www.vnitrnilekarstvi.eu/vnitrni-lekarstvi-clanek/co-je-noveho-v-srdecnim-selhani-se-zachovalou-ejekcni-frakci-leve-komory-za-poslednich-pet-let-49406
Field Cardiovascular diseases incl. cardiosurgery
Keywords diastolic dysfunction; heart failure; left ventricle; preserved ejection fraction of left ventricle
Description Heart failure with preserved ejection fraction of left ventricle (HFPEF) is frequent disease with serious consequences. Incidence of HFPEF in population still growing. The exact pathophysiological mechanism of HFPEF remain unclear. Recent evidence suggests a relationship between inflammation associated with obesity and diabetes mellitus and progression of HFPEF. Consistently it has been reported that serum concentration of some pro-inflamantory markers such as adiponectin is positively related to HFPEF. By HFPEF is attended diastolic dysfunction. Diastolic dyfunction is linked to many other cardiac and non-cardiac diseases. Despite the great effort and new therapeutic approaches the prognosis of HFPEF does not improve.

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