Publication details
Acne tetrada a možnosti biologické terapie
| Title in English | Acne tetrada and biological treatment options |
|---|---|
| Authors | |
| Year of publication | 2014 |
| Type | Article in Periodical |
| Magazine / Source | Dermatologie pro praxi |
| MU Faculty or unit | |
| Citation | |
| Field | Other medical specializations |
| Keywords | acne tetrada; biological treatment; TNF-alpha inhibitors; off-label |
| Description | Acne tetrada is a syndrom consisting of acne conglobata, hidradenitis suppurativa, perifolliculitis capitis abscedens et suffodiens and sinus pilonidalis. The conventional systemic therapy includes antibiotics, retinoids, imunosupressive therapy, peroral antidiabetics, sulphons, surgical methods and in women hormonal therapy. “Biological era“ reveals new methods of treatment. Besides psoriasis gets the harsh forms of acne to the point of interest of biological treatment nowadays. Acne is imunologically mediated desase with incerased levels of tumor necrosis factor alfa. Positive effect of therapy using anti TNF-alpha drugs (adalimumab, etanercept, infliximab) can be asumed. But in this indication the therapy is still in the phase of clinical trials, so we call it as “off-label“ treatment. |