Publication details

Metastázy jater a možnosti intervenční radiologie

Title in English Liver metastases, the role of interventional radiology
Authors

VÁLEK Vlastimil ANDRAŠINA Tomáš KISS Igor OSTŘÍŽKOVÁ Lenka

Year of publication 2015
Type Article in Periodical
Magazine / Source Onkologie
MU Faculty or unit

Faculty of Medicine

Citation
Field Other medical specializations
Keywords Chemoembolization; Colorectal cancer; DEBIRI; Drug-eluting beads; Liver metastases; Liver-directed therapy; Microwaves; RFA
Description Unresectable colorectal liver metastases have a 1- and 2-year survival of 55 % and 33 % with current systemic therapies. Currently image- -guided liver-directed therapy like trans-arterial chemoembolization (TACE), hepatic arterial infusion (HAI) and termoablation (RFA) has a growing role in the therapy of patients with liver metastases. Endovascular and percutaneous hepatic-directed therapy offers the dual benefit of true local neoplastic control and reduction of sideeffects. The development of new embolizing agents, such as DC beads (DEB) loaded with doxorubicin and irinotecan, permits better standardization and definition of protocols, making the procedures less linked to criteria of different hospitals and personal experiences of interventional radiologists.

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