Publication details
Carfilzomib and dexamethasone versus bortezomib and dexamethasone for patients with relapsed or refractory multiple myeloma (ENDEAVOR): a randomised, phase 3, open-label, multicentre study
Authors | |
---|---|
Year of publication | 2016 |
Type | Article in Periodical |
Magazine / Source | Lancet Oncology |
MU Faculty or unit | |
Citation | |
Doi | http://dx.doi.org/10.1016/S1470-2045(15)00464-7 |
Field | Oncology and hematology |
Keywords | END-POINTS; SURVIVAL; SAFETY |
Description | Background Bortezomib with dexamethasone is a standard treatment option for relapsed or refractory multiple myeloma. Carfilzomib with dexamethasone has shown promising activity in patients in this disease setting. The aim of this study was to compare the combination of carfilzomib and dexamethasone with bortezomib and dexamethasone in patients with relapsed or refractory multiple myeloma. Interpretation For patients with relapsed or refractory multiple myeloma, carfilzomib with dexamethasone could be considered in cases in which bortezomib with dexamethasone is a potential treatment option. |