Publication details
Cyanine-flavonol hybrids as NIR-light activatable carbon monoxide donors in methanol and aqueous solutions
| Authors | |
|---|---|
| Year of publication | 2022 |
| Type | Article in Periodical |
| Magazine / Source | Chemical Communications |
| MU Faculty or unit | |
| Citation | |
| Web | https://pubs.rsc.org/en/content/articlelanding/2022/CC/D2CC02648A |
| Doi | http://dx.doi.org/10.1039/d2cc02648a |
| Keywords | MECHANISMS; MOLECULES; ACID; DYES |
| Description | Here we report on carbon monoxide-photoreleasable compounds (photoCORMs) that combine heptamethine cyanine and flavonol chromophores and are activated upon irradiation with near-infrared light. Excellent CO-release yields and uncaging cross sections in aqueous solutions, enhanced water solubilities thanks to polar substituents or a host-guest approach using cucurbit[7]uril are demonstrated. The hybrids display outstanding biocompatibility and diverse, structure-dependent cell penetrability and internalization. |
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