Publication details

Výskyt infekce virem hepatitidy G (HGV) u pacientů léčených intravenózními imunoglobuliny v České republice

Title in English Prevalence of hepatitis G virus (HGV) in intravenous immunoglobulin recipients in the Czech Republic
Authors

SOBOTKOVÁ Marta BARTŮŇKOVÁ Jiřina LITZMAN Jiří ZACHOVÁ Radana JÍLEK Dalibor KRYŠTŮFKOVÁ Olga NĚMEČEK Vratislav VERNEROVÁ Eva ŠEDIVÁ Anna

Year of publication 2006
Type Article in Periodical
Magazine / Source Epidemiologie, Mikrobiologie, Imunologie
MU Faculty or unit

Faculty of Medicine

Citation
Field Immunology
Keywords hepatitis G virus; intravenous immunoglobuliny; common variable immunodeficiency; X-linked agammaglobulinemia
Description The prevalence of hepatitis G virus (HGV) in the serum of intravenous immunoglobulin (IVIG) recipients was studied and risk related to HGV positivity was considered. Although its pathogenicity is unclear, HGV is likely to cause liver disease or lymphoproliferation. Twenty (23%) of 86 tested MG patients were HGV RNA positive. Of the HGV positive patients, three (15%) showed mild elevation of liver enzymes and one (5%) was diagnosed with chronic lymphatic leukaemia prior to the institution of MG replacement. It can be concluded that the HGV prevalence among IVIG recipients is high but is not associated with signs of either liver disease or lymphoproliferation.
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