Publication details
Charakterizace bakteriofágů konvertujících Pantonův-Valentinův leukocidin u <I>Staphylococcus aureus</I>
| Title in English | Characterisation of Panton-Valentine leukocidin converting bacteriophages of <I>Staphylococcus aureus</I> |
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| Authors | |
| Year of publication | 2007 |
| Type | Article in Proceedings |
| Conference | XVI. konference mladých mikrobiologů Tomáškovy dny 2007 |
| MU Faculty or unit | |
| Citation | |
| Web | http://tomdny.fnusa.cz/ |
| Field | Genetics and molecular biology |
| Keywords | Community acquired Staphylococcus aureus; MRSA; bacteriophage; PVL |
| Description | Staphylococcus aureus is a major cause of severe community-acquired and nosocomial infections. Much of the dissimilarity between S. aureus pathogenic strains is dependent on the presence of virulence factors encoded on mobile genetic elements, such as pathogenicity islands and bacteriophages. One of these factors is the Panton-Valentine leukocidin (PVL). It is a bi-component toxin produced by S. aureus isolates that are associated with lethal necrotizing pneumonia, severe skin and invasive infections. Recently were isolated several temperate phages, which carry the genes encoding the PVL proteins (lukS-PV and lukF-PV). The aim of this study was to characterize the PVL converting bacteriophages from community acquired isolates of S. aureus in the Czech Republic. |
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