On-capillary microreaction electrophoretic technique utilizing microsomes as an enzymatic system in drug metabolism studies

• Authors: ZEISBERGEROVÁ Marta; KONEČNÝ Jiří; GLATZ Zdeněk; HOOGMARTENS Jos; VAN SCHEPDAEL Ann
• Year of publication: 2008
• Type: Article in Proceedings
• Conference: XII. Setkání biochemiků a molekulárních biologů
• MU Faculty or unit: Faculty of Science
• Field: Biochemistry
• Keywords: drug metabolism; microsomes; on-capillary microreaction; electrophoresis
• Description: Drug metabolism studies performed by the mean of on-capillary microreaction by electrophoretic technique. Enzymatic system of Phase I of biotransformation comprising microsomes as the main source of cytochromes P450 was utilized for examined microreactions.

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