TRITON: a graphical tool for ligand-binding protein engineering

• Authors: PROKOP Martin; ADAM Jan; KŘÍŽ Zdeněk; WIMMEROVÁ Michaela; KOČA Jaroslav
• Year of publication: 2008
• Type: Article in Periodical
• Magazine / Source: Bioinformatics
• MU Faculty or unit: Faculty of Science

Web

• Abstract and full text (open access artcle)
• Web page of the program TRITON

• Field: Biochemistry
• Keywords: software development; protein engineering; protein-ligand docking
• Description: Summary: The new version of the TRITON program provides user-friendly graphical tools for modeling protein mutants using the external program MODELLER and for docking ligands into the mutants using the external program AutoDock. TRITON can now be used to design ligand-binding proteins, to study protein-ligand binding mechanisms or simply to dock any ligand to a protein. Availability: Executable files of TRITON are available free of charge for academic users at http://ncbr.chemi.muni.cz/triton/ Contact: [e-mail] Supplementary information: Supplementary data are available at Bioinformatics online.

Related projects

• Proteins in metabolism and interaction of organisms with the environment
• Structure-function studies on lectins and adhesins from microbial patogens
• Biomolecular centre