Publication details

HAPLOTYPE OF FOUR MMP2 GENE PROMOTER POLYMORPHISMS AS PROTECTION VARIANT FOR ISCHEMIC HEART DISEASE AHEAD OF PROGRESSION TO HEART FAILURE

Authors

PÁVKOVÁ GOLDBERGOVÁ Monika POLOCZEK Martin PAŘENICA Jiří ŠPINAROVÁ Lenka GROCH Ladislav ŠPINAR Jindřich VAŠKŮ Anna

Year of publication 2008
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description The study detected differences in genotype distributions and/or alelle frequences of MMP2 -790G/T polymorphism between patients with chronic heart failure on base of IHD and IHD patients (Pg=0.001, OR=3.07; Pa=0.01). Further, highly significant association in haplotype frequences was observed between chronic heart failure on base of IHD and IHD patients (Pg=0.0014), with higer prevalence of GCGC haplotype within the CHF group (OR=29,51; P=0.000001).
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