Publication details
SYNTHESIS OF NEW 1-SUBSTITUTED 4-(2-PHENYLQUINAZOLIN-4-YL)- AND 4-(2-PHENYLQUINAZOLIN-4-YLIDENE) THIOSEMICARBAZIDES
| Authors | |
|---|---|
| Year of publication | 2008 |
| Type | Article in Periodical |
| Magazine / Source | Chemistry of Heterocyclic Compounds |
| MU Faculty or unit | |
| Citation | |
| Field | Organic chemistry |
| Keywords | quinazoline; thiosemicarbazide; domino reaction; hydrogen bond interaction |
| Description | Two new 1-substituted 4-(2-phenylquinazolin-4-yl)- and 4-(2-phenylquinazolin-4-ylidene) thio-semicarbazides were formed by a multistep domino reaction of imidoyl isothiocyanate derivative with 1,1-di-R-hydrazine in acetone solution. Application of hydrazine hydrate under the same reaction conditions afforded 4-(2-phenylquinazolin-4(3H)-ylidene)-2-(propen-2-yl)-1-(propan-2-ylidene) thio-semicarbazide via a six-step triple-component domino reaction. |
| Related projects: |