Publication details

Abnormální metabolizmus thiaminu u DM jako důsledek funkčního deficitu pentózového cyklu a vztah k progresi diabetické nefropatie a mortalitě

Title in English Abnormal thiamin metabolism caused by functional deficit of pentose phoshate cycle and relation to progression of diabetic nephropathy and mortality
Authors

KRUSOVÁ Darja PÁCAL Lukáš KAŇKOVÁ Kateřina SVOJANOVSKÝ Jan TOMANDL Josef OLŠOVSKÝ Jindřich

Year of publication 2010
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description The results support the role of functional thiamine deficiency in the development of hyperglycaemia- related pathology. Limited intracellular availability of active TKT co-factor seems to be a dominant abnormality.
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