Publication details

A new quantitative description of intracellular Ca2+ dynamics in the model of rat ventricular myocyte

Authors

PÁSEK Michal ŠIMURDA Jiří

Year of publication 2011
Type Article in Proceedings
Conference Engineering Mechanics 2011
MU Faculty or unit

Faculty of Medicine

Citation
Field Biophysics
Keywords cardiac cell; ICa; mathematical model
Attached files
Description The paper presents a new description of intracellular Ca2+ dynamics in the model of rat ventricular myocyte. The principal modifications based on the recently published data comprise: formulation of the function of peripheral dyads, incorporation of peripheral and tubular intracellular subspaces, reformulation of inactivation properties of surface of tubular ICa and description of the function of exogenous Ca2+ buffer in the intracellular space.
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