Publication details

Současné možnosti výběru spermie v asistované reprodukci

Title in English Advanced methods of sperm selection in assisted reproduction
Authors

CRHA Igor ŽÁKOVÁ Jana

Year of publication 2012
Type Article in Periodical
Magazine / Source Moderní gynekologie a porodnictví
MU Faculty or unit

Faculty of Medicine

Citation
Field Gynaecology and obstetrics
Keywords assisted reproductive techniques; hyaluronic acid binding; magnetic cell sorting; sperm selection
Attached files
Description Current routine semen preparation techniques do not target all intrinsic sperm characteristics that may impact the fertilization potential. Several methods have been recently developed and applied to sperm selection. Current advanced sperm selection methods are based on surface charge (electrophoresis and zeta potential), apoptosis (magnetic cell sorting and glass wool), membrane maturity (hyaluronic acid binding) and ultramorphology (high magnification). Selection of high-quality sperm including improvements in DNA integrity could improve fertilization and pregnancy rates.
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