Mgr. Šárka Pavlová, Ph.D.

2025

• Detection of clinically relevant variants in the TP53 gene below 10% allelic frequency: A multicenter study by ERIC, the European Research Initiative on CLL

  PAVLOVÁ Šárka MALČÍKOVÁ Jitka RADOVÁ Lenka BONFIGLIO Silvia COWLAND Jack B BRIEGHEL Christian ANDERSEN Mette K KARYPIDOU Maria BIDERMAN Bella DOUBEK Michael LAZARIAN Gregory RAPADO Inmaculada VYNCK Matthijs PORRET Naomi A ANDRES Martin ROSENBERG Dina SAHAR Dvora MARTINEZ-LAPERCHE Carolina BUNO Ismael HINDLEY Andrew DONALDSON David SANCHEZ Julio B GARCIA-MARCO Jose A SERRANO-ALCALA Alicia FERRER-LORES Blanca FERNANDEZ-RODRIGUEZ Concepcion BELLOSILLO Beatriz STILGENBAUER Stephan TAUSCH Eugen NIKDIN Hero QUINN Fiona ATKINSON Emer LISETTE van de Corput YILDIZ Cafer BILBAO-SIEYRO Cristina FLORIDO Yanira THIEDE Christian SCHUSTER Caroline STOJ Anastazja CZEKALSKA Sylwia CHATZIDIMITRIOU Anastasia LAIDOU Stamatia BIDET Audrey DUSSIAU Charles NOLLET Friedel PIRAS Giovanna MONNE Maria SMIRNOVA Svetlana NIKITIN Eugene SLOMA Ivan CLAUDEL Alexis LARGEAUD Laetitia YSEBAERT Loic VALK Peter J M CHRISTIAN Amy WALEWSKA Renata OSCIER David SEBASTIAO Marta GOMES da Silva Maria GALIENI Piero ANGELINI Mario ROSSI Davide SPINA Valeria MATOS Sonia MARTINS Vania STOKLOSA Tomasz PEPEK Monika BALIAKAS Panagiotis ANDREU Rafa LUNA Irene KAHRE Tiina MURUMETS Ulle PIKOUSOVA Tereza KURUCOVA Terezia LAIRD Sophie WARD Daniel ALCOCEBA Miguel BALANZATEGUI Ana SCARFO Lydia GANDINI Francesca ZAPPAROLI Ettore BLANCO Adoracion ABRISQUETA Pau RODRIGUEZ-VICENTE Ana E BENITO Rocio BRAVETTI Clotilde DAVI Frederic GAMEIRO Paula MARTINEZ-LOPEZ Joaquin TAZON-VEGA Barbara BARAN-MARSZAK Fanny DAVIS Zadie CATHERWOOD Mark SUDARIKOV Andrey ROSENQUIST Richard NIEMANN Carsten U STAMATOPOULOS Kostas GHIA Paolo POSPÍŠILOVÁ Šárka

  Article in Periodical

  HemaSphere, year: 2025, volume: 9, edition: 1, DOI

• Hypomethylating agents increase L1 retroelement expression without inducing novel insertions in myeloid malignancies

  PAVLOVÁ Šárka SVOZILOVÁ Hana KRZYŽÁNKOVÁ Marcela SONNEK Radim VOLAKHAVA Anastasiya SMIRNOVA Anastasia GRIGOREVA Tatiana JAŠKOVÁ Zuzana SYNACKOVA Hana WAHL Dennis BILČÍKOVÁ Michaela ČERVINEK Libor POSPÍŠILOVÁ Šárka MAMEDOV Ilgar PLEVOVÁ Karla

  Article in Periodical

  Molecular oncology, year: 2025, DOI

• In-frame germline TP53 variant impairs p53 oligomerization and predisposes to cancer

  VANIKOVA Lucie MACHACKOVA Eva NEMCOVA Barbora SOUKUPOVA Jana PETREZSELYOVA Silvia NOVAKOVA Klara ŽENATOVÁ Marcela PAVLOVÁ Šárka KLEIBLOVA Petra KLEIBL Zdenek FORETOVA Lenka MACUREK Libor

  Article in Periodical

  Nature Scientific Reports, year: 2025, volume: 15, edition: 1, DOI

2024

• Are del(17p) with concurrent TP53 mutation, and isolated TP53 mutation really equivalent?

  POSPÍŠILOVÁ Šárka MALČÍKOVÁ Jitka PAVLOVÁ Šárka

  Conference abstract

  Year: 2024, type: Conference abstract

• Biomarker-guided treatment of CLL: where do we go from here?

  PAVLOVÁ Šárka

  Requested lectures

  Year: 2024, type: Requested lectures

• Dysregulation of the p53 pathway provides a therapeutic target in aggressive pediatric sarcomas with stem-like traits

  CURYLOVÁ Lucie ZAMBO Iva NERADIL Jakub KÝR Michal JURAČKOVÁ Nicola PAVLOVÁ Šárka POLÁŠKOVÁ Kristýna MÚDRY Peter ŠTĚRBA Jaroslav VESELSKÁ Renata ŠKODA Jan

  Article in Periodical

  CELLULAR ONCOLOGY, year: 2024, volume: 47, edition: 6, DOI

• ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-2024 update

  MALČÍKOVÁ Jitka PAVLOVÁ Šárka BALIAKAS Panagiotis CHATZIKONSTANTINOU Thomas TAUSCH Eugen CATHERWOOD Mark ROSSI Davide SOUSSI Thierry TICHÝ Boris KATER Arnon P NIEMANN Carsten U DAVI Frederic GAIDANO Gianluca STILGENBAUER Stephan ROSENQUIST Richard STAMATOPOULOS Kostas GHIA Paolo POSPÍŠILOVÁ Šárka

  Article in Periodical

  Leukemia, year: 2024, volume: 38, edition: 7, DOI

• In-frame varianty genu TP53 nalezené v leukemických buňkách dospělých pacientů vedou ke ztrátě proteinu: mezinárodní studie

  PAVLOVÁ Šárka GOMBÍKOVÁ Johana ŽENATOVÁ Marcela SKUHROVÁ FRANCOVÁ Hana ZAPLETALOVÁ Eva JEŽÍŠKOVÁ Ivana ČINÁTLOVÁ Klára MALČÍKOVÁ Jitka POSPÍŠILOVÁ Šárka

  Conference abstract

  Year: 2024, type: Conference abstract

• Integrative NGS testing reveals clonal dynamics of adverse genomic defects contributing to a natural progression in treatment-naïve CLL patients

  NAVRKALOVÁ Veronika PLEVOVÁ Karla RADOVÁ Lenka PORC Jakub Paweł PÁL Karol MALČÍKOVÁ Jitka PAVLOVÁ Šárka DOUBEK Michael PANOVSKÁ Anna KOTAŠKOVÁ Jana POSPÍŠILOVÁ Šárka

  Article in Periodical

  British journal of haematology, year: 2024, volume: 204, edition: 1, DOI

• KLONÁLNÍ KOMPETICE A ALTERACE MOLEKULÁRNÍCH DRAH U CHRONICKÉ LYMFOCYTÁRNÍ LEUKEMIE

  TAUŠOVÁ Kristýna PORC Jakub Paweł TAUŠ Petr PÁL Karol PAVLOVÁ Šárka MALČÍKOVÁ Jitka STRÁNSKÁ Kamila ŽENATOVÁ Marcela TICHÝ Boris PANOVSKÁ Anna DOUBEK Michael POSPÍŠILOVÁ Šárka PLEVOVÁ Karla

  Conference abstract

  Year: 2024, type: Conference abstract