doc. Ing. Vlad Popovici, PhD

2025

• A phase Ia study of the MEK1/2 inhibitor PD-0325901 with the c-MET inhibitor crizotinib in patients with advanced solid cancers

  GALLAGHER Peter ROLFO Christian ELEZ Elena TAIEB Julien HOULDEN Jennifer COLLINS Linda ROBERTS Corran ANDRE Thierry LAWLER Mark DI NICOLANTONIO Federica GRAYSON Margaret BOYD Ruth POPOVICI Vlad BARDELLI Alberto CARSON Robbie KHAWAJA Hajrah LAURENT-PUIG Pierre SALTO-TELLEZ Manuel HENNESSY Bryan T. MAUGHAN Tim S. TABERNERO Josep ADAMS Richard JONES Robert PEETERS Marc MIDDLETON Mark R. WILSON Richard H. VAN SCHAEYBROECK Sandra CONSORTIUM MErCuRIC Trial

  Article in Periodical

  BJC REPORTS, year: 2025, volume: 3, edition: 1, DOI

• A Phase Ia/b study of MEK1/2 inhibitor binimetinib with MET inhibitor crizotinib in patients with RAS mutant advanced colorectal cancer (MErCuRIC)

  AROLDI Francesca ELEZ Elena ANDRE Thierry PERKINS Geraldine PRENEN Hans POPOVICI Vlad GALLAGHER Peter HOULDEN Jennifer COLLINS Linda ROBERTS Corran ROLFO Christian DI NICOLANTONIO Federica GRAYSON Margaret BOYD Ruth BETTENS Karolien DELFAVERO Jurgen COYLE Victoria LAWLER Mark KHAWAJA Hajrah LAURENT-PUIG Pierre SALTO-TELLEZ Manuel MAUGHAN Tim S. TABERNERO Josep ADAMS Richard JONES Robert HENNESSY Bryan T. BARDELLI Alberto PEETERS Marc MIDDLETON Mark R. WILSON Richard H. VAN SCHAEYBROECK Sandra

  Article in Periodical

  BMC Cancer, year: 2025, volume: 25, edition: 1, DOI

• A quantitative tumor-wide analysis of morphological heterogeneity of colorectal adenocarcinoma

  DRAGOMIR Mihnea P. POPOVICI Vlad SCHALLENBERG Simon ČARNOGURSKÁ Martina HORST David NENUTIL Rudolf BOSMAN Fred BUDINSKÁ Eva

  Article in Periodical

  JOURNAL OF PATHOLOGY CLINICAL RESEARCH, year: 2025, volume: 11, edition: 4, DOI

• Impact of the ONCOBIOME network in cancer microbiome research

  ZITVOGEL Laurence DEROSA Lisa ROUTY Bertrand LOIBL Sibylle HEINZERLING Lucie DE VRIES I. Jolanda M. ENGSTRAND Lars SEGATA Nicola KROEMER Guido ALVES COSTA SILVA Carolina BARBIERI Daniela BOLEIJ Annemarie BOL Kalijn BRUSSELAERS Nele BUDINSKÁ Eva CALDAS Carlos CORDERO Francesca CREMOLINI Chiara DAILLERE Romain DENKERT Carsten DURAND Sylvere EHRLICH Stanislav EISINGER François ELKRIEF Arielle FALL Katja FELDER Baerbel FERRERE Gladys FIDELLE Marine GABORIT Jérôme GARIBOLDI Manuela GUINDO Cheick Oumar IEBBA Valerio LEHTIO Janne MARTINEAU Magalie MESSAOUDENE Meriem MONVILLE Florence NACCARATI Alessio PARDINI Barbara PINTO Federica PICCINNO Gianmarco PIZZATO Eugénie POPOVICI Vlad RACHID Maan Haj TARALLO Sonia SCHULER-THURNER Beatrice SCHULER Gerold SZALLASI Zoltan SOW Cissé TRINCHIERI Giorgio TROCHON Jean-Jacques ZELLER Georg

  Article in Periodical

  Nature Medicine, year: 2025, volume: 31, edition: 4, DOI

• Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer

  PICCINNO Gianmarco THOMPSON Kelsey N. MANGHI Paolo GHAZI Andrew R. THOMAS Andrew Maltez BLANCO-MIGUEZ Aitor ASNICAR Francesco MLADENOVIC Katarina PINTO Federica ARMANINI Federica PUNCOCHAR Michal PIPERNI Elisa HEIDRICH Vitor FACKELMANN Gloria FERRERO Giulio TARALLO Sonia NGUYEN Long H. YAN Yan KELES Nazim A. TUNA Bilge G. VYMETALKOVA Veronika TROMPETTO Mario LISKA Vaclav HUCL Tomas VODICKA Pavel BENCSIKOVA Beatrix ČARNOGURSKÁ Martina POPOVICI Vlad MARMORINO Federica CREMOLINI Chiara PARDINI Barbara CORDERO Francesca SONG Mingyang CHAN Andrew T. DEROSA Lisa ZITVOGEL Laurence HUTTENHOWER Curtis NACCARATI Alessio BUDINSKÁ Eva SEGATA Nicola

  Article in Periodical

  Nature Medicine, year: 2025, volume: 31, edition: 7, DOI

• Search for Mutations Connected With Non-Response to Anti-EGFR Therapy in mCRC in the Morphologically Defined Regions of Primary Tumours

  ČARNOGURSKÁ Martina VASYLIEVA Valeriia Serhiivna MACHÁČKOVÁ Táňa BOUDNÁ Marie PIFKOVÁ Lucie ORLÍČKOVÁ Jana CATELA IVKOVIĆ Tina SLABÝ Ondřej BENCSIKOVA Beatrix POPOVICI Vlad BUDINSKÁ Eva

  Article in Periodical

  Cancer Medicine, year: 2025, volume: 14, edition: 9, DOI

2024

• An invasion front gene expression signature for higher-risk patient selection in stage IIA MSS colon cancer

  BUDINSKÁ Eva ČARNOGURSKÁ Martina CATELA IVKOVIĆ Tina MACHÁČKOVÁ Táňa BOUDNÁ Marie PIFKOVÁ Lucie SLABÝ Ondřej BENCSIKOVA Beatrix POPOVICI Vlad

  Article in Periodical

  Frontiers in Oncology, year: 2024, volume: 14, edition: April 2024, DOI

2023

• IntOMICS: A Bayesian Framework for Reconstructing Regulatory Networks Using Multi-Omics Data

  PAČÍNKOVÁ Anna POPOVICI Vlad

  Article in Periodical

  Journal of Computational Biology, year: 2023, volume: 30, edition: 5, DOI

• Molecular portraits of colorectal cancer morphological regions

  BUDINSKÁ Eva HRIVŇÁKOVÁ Martina CATELA IVKOVIĆ Tina BOUDNÁ Marie NENUTIL Rudolf BENCSIKOVÁ Beatrix AL TUKMACHI Dagmar RUČKOVÁ Michaela DUBSKÁ Lenka SLABÝ Ondřej FEIT Josef MIHNEA-PAUL Dragomir BOŘILOVÁ LINHARTOVÁ Petra TEJPAR Sabine POPOVICI Vlad

  Article in Periodical

  eLife, year: 2023, volume: 12, edition: Nov, DOI

• Next generation proteomics identifies a potential protein marker of poor response to tyrosine kinase inhibitors in metastatic renal cell carcinoma

  BOUCHALOVÁ Pavla ŠIMONÍK Jan LAPČÍK Petr JANÁČOVÁ Lucia POTĚŠIL David PODHOREC Ján HLOBILKOVÁ Alice POPOVICI Vlad HORA Milan POPRACH Alexandr FIALA Ondřej BOUCHAL Pavel

  Conference abstract

  Year: 2023, type: Conference abstract