prof. Mgr. Jiří Damborský, Dr.

2023

• Advancing Enzyme's Stability and Catalytic Efficiency through Synergy of Force-Field Calculations, Evolutionary Analysis, and Machine Learning

  KUNKA Antonín MARQUES Sérgio Manuel HAVLÁSEK Martin VAŠINA Michal VELÁTOVÁ Nikola CENGELOVÁ Lucia KOVÁŘ David DAMBORSKÝ Jiří MAREK Martin BEDNÁŘ David PROKOP Zbyněk

  Article in Periodical

  ACS Catalysis, year: 2023, volume: 13, edition: 19, DOI

• Catalytic mechanism for Renilla-type luciferases

  SMITH Andrea TOUL Martin PLUSKAL Daniel BAATALLAH Racha GAGNOT Glwadys RANGEL PAMPLONA PIZARRO PINTO José Gaspar SANTANA Vinicius T. T. STUCHLÁ Markéta NEUGEBAUER Petr CHAIYEN Pimchai DAMBORSKÝ Jiří BEDNÁŘ David JANIN Yves L. L. PROKOP Zbyněk MAREK Martin

  Article in Periodical

  Nature Catalysis, year: 2023, volume: 6, edition: 1, DOI

• Deciphering Enzyme Mechanisms with Engineered Ancestors and Substrate Analogues

  GAO Tadeja DAMBORSKÝ Jiří JANIN Yves L. MAREK Martin

  Article in Periodical

  ChemCatChem, year: 2023, volume: 15, edition: 19, DOI

• Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate

  NEMERGUT Michal MARQUES Sérgio Manuel UHRÍK Lukáš VÁŇOVÁ Tereza NEZVEDOVÁ Markéta GADARA Darshak Chandulal JHA Durga TULIS Jan NOVÁKOVÁ Veronika PLANAS IGLESIAS Joan KUNKA Antonín LEGRAND Anthony Thomas P HŘÍBKOVÁ Hana POSPÍŠILOVÁ Veronika SEDMÍK Jiří RAŠKA Jan PROKOP Zbyněk DAMBORSKÝ Jiří BOHAČIAKOVÁ Dáša SPÁČIL Zdeněk HERNYCHOVÁ Lenka BEDNÁŘ David MAREK Martin

  Article in Periodical

  Molecular Neurodegeneration, year: 2023, volume: 18, edition: 1, DOI

• ChannelsDB 2.0: A Comprehensive Database of Protein Tunnels and Pores in AlphaFold Era

  ŠPAČKOVÁ Anna VÁVRA Ondřej RAČEK Tomáš BAZGIER Václav SEHNAL David DAMBORSKÝ Jiří SVOBODOVÁ Radka BERKA Karel

  Conference abstract

  Year: 2023, type: Conference abstract

• ChannelsDB 2.0: a comprehensive database of protein tunnels and pores in AlphaFold era

  ŠPAČKOVÁ Anna VÁVRA Ondřej RAČEK Tomáš BAZGIER Václav SEHNAL David DAMBORSKÝ Jiří SVOBODOVÁ Radka BEDNÁŘ David BERKA Karel

  Article in Periodical

  Nucleic Acids Research, year: 2023, DOI

• Identification, characterization, and engineering of glycosylation in thrombolytics

  TOUL Martin SLONKOVÁ Veronika MIČAN Jan URMINSKÝ Adam Paulin TOMKOVA Maria SEDLÁK Erik BEDNÁŘ David DAMBORSKÝ Jiří HERNYCHOVÁ Lenka PROKOP Zbyněk

  Article in Periodical

  Biotechnology Advances, year: 2023, volume: 66, edition: September 2023, DOI

• In-depth analysis of biocatalysts by microfluidics: An emerging source of data for machine learning

  VAŠINA Michal KOVÁŘ David DAMBORSKÝ Jiří YUN Ding YANG Tianjin DE MELLO Andrew MAZURENKO Stanislav STAVRAKIS Stavros PROKOP Zbyněk

  Article in Periodical

  Biotechnology Advances, year: 2023, volume: 66, edition: September 2023, DOI

• Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography

  CHMELOVÁ Klaudia GAO Tadeja POLÁK Martin SMITH Andrea CROLL Tristan I. SHAIKH Tanvir R. ŠKAŘUPOVÁ Jana CHALOUPKOVÁ Radka DIEDERICHS Kay READ Randy J. DAMBORSKÝ Jiří NOVÁČEK Jiří MAREK Martin

  Article in Periodical

  Protein Science, year: 2023, volume: 32, edition: 10, DOI

• Pathogenesis of Alzheimer´s disease: Involvement of the choroid plexus

  ČARNA Maria ONYANGO Isaac G. KATINA Stanislav HOLUB Dušan NOVOTNY Jan Sebastian NEZVEDOVÁ Markéta JHA Durga NEDELSKA Zuzana LACOVICH Valentina VYVERE Thijs Vande HOUBRECHTS Ruben GARCIA-MANSFIELD Krystine SHARMA Ritin DAVID-DIRGO Victoria VYHNALEK Martin TEXLOVA Kateřina CHAVES Hernan BAKKAR Nadine PERTIERRA Lucia VINKLER Mojmír MARKOVA Hana LACZO Jan SHEARDOVÁ Kateřina HORTOVA-KOHOUTKOVA Marcela FRIČ Jan FORTE Giancarlo KAŇOVSKY Petr BELAŠKOVA Silvie DAMBORSKÝ Jiří HORT Jakub SEYFRIED Nicholas T. BOWSER Robert SEVLEVER Gustavo RISSMAN Robert A. SMITH Richard A. HAJDUCH Marian PIRROTTE Patrick SPÁČIL Zdeněk DAMMER Eric B. LIMBÄCK-STOKIN Clara STOKIN Gorazd B.

  Article in Periodical

  Alzheimer´s & Dementia, year: 2023, volume: 19, edition: 8, DOI