Publication details
Gorlinův syndrom
| Title in English | Gorlin syndrome |
|---|---|
| Authors | |
| Year of publication | 2013 |
| Type | Article in Periodical |
| Magazine / Source | Česká dermatovenerologie |
| MU Faculty or unit | |
| Citation | |
| Field | Dermatovenerology |
| Keywords | Hedgehog signal pathway; PTCH gene; basal cell carcinoma; malformations |
| Description | Corlin syndrome is a multiorgan disease, caused by a mutation in the Hedgehog signal pathway. The therapeutic approach involves topical, surgical and systemic symptomatic therapy. Targeted therapy has been approved in USA. |