Publication details

Srovnání opioidní a neopioidní analgezie po císařském řezu v celkové anestezii – prospektivní observační studie.

Title in English	Comparison of opioid and non-opioid analgesia after Caesarean Section under general anesthesia: a prospective observational study
Authors	ŠTOURAČ Petr SEIDLOVÁ Dagmar BÁRTÍKOVÁ Ivana KUCHAŘOVÁ Eliška JANKŮ Petr KŘIKAVA Ivo HUSER Martin WÁGNEROVÁ Kristýna HAKLOVÁ Olga HAKL Lubomír ŠTOUDEK Roman KOSINOVÁ Martina SCHWARZ Daniel ZELINKOVÁ Hana ŠEVČÍK Pavel GÁL Roman
Year of publication	2014
Type	Article in Periodical
Magazine / Source	Anesteziologie a intenzivní medicína
MU Faculty or unit	Faculty of Medicine
Citation
Field	Gynaecology and obstetrics
Keywords	acute pain service; pain management; postoperative analgesia; Caesarean Section; opioids; non-opioids; obstetrics; general anesthesia
Description	Objective: The aim of the prospective observational study was to determine efficacy of opioid compared to non-opioid analgesics in postcaesarean pain management. Design: Prospective observational study Setting: University Hospital Material and Methods: For the Non-opioid group (NO) we used a combination of paracetamol 1000 mg IV or PO and diclofenac 100 mg rectally or IM at predefined times. For the Opioid group (OP) we used piritramide 3 mg per hour IV continuously. Additional metamizole 2.5g IV was administered as a rescue analgesic therapy for both groups. We recorded Visual Analogue Scale (VAS), the Additional Analgesics Requests (AAR) and complications during the postcaesarean period. We compared VAS values and number of AARs in both groups in the first 24 hours after Caesarean Section (CS). Results: With the Ethics Committee Approval, we enrolled 160 patients (NO, N=120; OP, N=40) after CS under general anesthesia in the period May 2009 - April 2010. The median VAS score in the first hour after CS was 3.5 in both groups (p=0.553). There were statistically significant differences in VAS level and number of AARs between 1st and 24th hour after CS (p <0.001). There were no serious complications recorded. Conclusion: We conclude sufficient analgesic effect (VAS under 4) in both study groups with better effect of the opioid analgesics in the first postoperative day.