Publication details

Etravirin v klinické praxi

Title in English Etravirine in clinical practice
Authors

JILICH David ROZSYPAL Hanuš ZJEVÍKOVÁ Alena SEDLÁČEK Dalibor SNOPKOVÁ Svatava MACHALA Ladislav

Year of publication 2014
Type Article in Periodical
Magazine / Source Klinická farmakologie a farmacie
MU Faculty or unit

Faculty of Medicine

Citation
Field Epidemiology, infectious diseases and clinical immunology
Keywords etravirine; HIV; NNRTI; cART
Description Since the mid-nineties of the last century, combination antiretroviral therapy has been the main treatment strategy for HIV. Reverse transcriptase inhibitors are among the traditionally used drug classes. Etravirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI). Due to the need to combine drugs from different classes, each newly approved medicinal product is an option for patients with resistance or intolerance to previous therapy. Etravirine is generally characterized by high efficacy, a low risk of side effects and a higher resistance barrier in comparison with first-generation NNRTIs.

You are running an old browser version. We recommend updating your browser to its latest version.

More info