Publication details
Dítě s imunodeficientním stavem, možnosti řešení. 2. část, Léčba a novorozenecký screening
| Authors | |
|---|---|
| Year of publication | 2014 |
| Type | Article in Periodical |
| Magazine / Source | Pediatrie pro praxi |
| MU Faculty or unit | |
| Citation | |
| Field | Immunology |
| Keywords | imunodeficiency; IVIG; SCIG; TREC; KREC; transplantation; dried blood spot; screening |
| Description | Early diagnosis of immunodeficiency makes possible early definitive therapy and avoids the complications of pretreatment infections. T-cell immunodeficiency defects become apparent as combined T- and B-cell deficiencies. Therefore, implementation of TRECs and KRECs into the newborn screening from dried blood spot will increase the preventive approach to early immunodeficiency diagnostics. Infants undergoing transplantation in the first 3 months of life have a much higher rate of survival than those undergoing transplantation later. |