Publication details

Umbilical Cord Tissue-Derived Cells as Therapeutic Agents

Authors

MASLOVA Olga NOVÁK Miroslav KRUŽLIAK Peter

Year of publication 2015
Type Article in Periodical
Magazine / Source Stem Cells International
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.1155/2015/150609
Field Genetics and molecular biology
Keywords MESENCHYMAL STEM-CELLS; NEURONS IN-VITRO; STROMAL CELLS; CLINICAL-APPLICATIONS; REGENERATIVE MEDICINE; PHENOTYPIC CHARACTERIZATION; IMMUNOMODULATORY PROPERTIES; DIFFERENTIATIVE CAPACITY; IMMUNOLOGICAL-PROPERTIES; AUTOIMMUNE-DISEASES
Description Although the characteristics of SC, including UC-derived cells, are a dramatically discussed issue, this review will focus particularly on some controversial issues regarding clinical utility of cells isolated from UC tissue. UC-derived cells have several advantages compared to other types and sources of stem cells. The impact of UC topography on cell characteristics is briefly discussed. The necessity to adapt existing methods of cell isolation and culturing to GMP conditions is mentioned, as well as possible cryopreservation of this material. Light is shed on some future perspectives for UC-derived cells.

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