Publication details

Diagnostika a léčba plicní formy histiocytózy z langerhansových buněk

Title in English Diagnosis and treatment of pulmonary Langerhans cell histiocytosis
Authors

DOUBKOVÁ Martina ADAM Zdeněk DOUBEK Michael HORVÁTH Teodor POUR Luděk ŘEHÁK Z. KOUKALOVÁ Renata KRÁL Zdeněk

Year of publication 2020
Type Article in Periodical
Magazine / Source Studia pneumologica et phtiseologica
MU Faculty or unit

Faculty of Medicine

Citation
Web web
Keywords Langerhans cell histiocytosis smoking genes cladribine vinblastine
Description Pulmonary Langerhans cell histiiocystosis is a rare discorder that occurs minly in young smokers. i is characterized by proliferation and infiltration of Langerhans cells in the lungs. The etiology is unknown, but in some cases, mutations i the BRAF or NRAS, KRAS and MAP2K1 genes may be found. The disease may resolve spntaneusly or require systemic corticosteroid or cytostatic druh therapy. The authors present their experience with the disease and also provide X-ray documentation.

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