Publication details
Účinnost hyperbarické oxygenoterapie u neuropatických a neuroischemických diabetických ulcerací nohy: protokol systematického review typu „umbrella“
| Title in English | Effectiveness of hyperbaric oxygen therapy in neuropathic and neuroischemic diabetic foot ulcer: an umbrella review protocol |
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| Authors | |
| Year of publication | 2020 |
| Type | Article in Periodical |
| Magazine / Source | Zdravotnícké Listy |
| MU Faculty or unit | |
| Citation | |
| Web | https://zl.tnuni.sk/fileadmin/Archiv/2020/2020-8.c.4/ZL_2020_8_4_05_Klugar2.pdf |
| Keywords | Hyperbaric oxygen therapy; Non-healing ulcers; Diabetic foot ulcer; Meta-analysis; Umbrella review |
| Description | Background: Neuropathic and neuroischemic diabetic foot ulcerations (DFU) are usually associated with hypoxia, poor perfusion and low oxygen consumption. Hyperbaric oxygen therapy (HBOT) leads to hyperoxygenation, and multiple increases in oxygen partial pressure in both blood and tissues occurs, thus improving healing. Objective: The objective of this umbrella systematic review will be to investigate the effectiveness of HBOT in neuropathic and neuroischemic diabetic ulcerations. Inclusion criteria: Population - the patients of all ages with diabetes suffering from chronic neuropathic or neuroischemic non-healing wounds will be included. Intervention - hyperbaric Oxygen Therapy. Comparison - standard therapy (any alternative therapy). Outcomes - standardized measures of effectiveness of the intervention for wound healing (hyperoxia, TpC02, ischemic parameters, duration of healing, wound reduction, local wound symptomatology - (exudate, pain, wound bed) and HRQoL). Systematic reviews will be included. Methods: We will follow the methodology of the Joanna Briggs Institute for umbrella reviews. We will search ten databased by the Epistemonikos platform to identify any relevant systematic reviews. No language or geographical limit will be applied. Two independent reviewers will carry out screening, critical appraisal, and data extraction. The certainty of evidence will be assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. |