Publication details
Způsob přípravy konjugátů s řízenou rychlostí uvolňování léčiva s nosiči protinádorového léčiva na bázi selektivně oxidovaných polysacharidů
| Title in English | Method of preparing conjugates with a controlled release rate of the drug with antitumor drug carriers based on selectively oxidized polysaccharides |
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| Authors | |
| Year of publication | 2022 |
| Type | Patent |
| MU Faculty or unit | |
| Publisher | Úřad průmyslového vlastnictví |
| State | Czech Republic |
| Patent's number | 309355 |
| Web | https://isdv.upv.cz/webapp/resdb.print_detail.det?pspis=PT/2018-461&plang=CS |
| Attached files | |
| Description | The solution relates to a method of preparing 2,3-dicarboxypolysaccharides with controllable molecular weight, optionally modified with biologically active ligands, usable as carriers of antitumor drugs. These are antitumor drugs based on transition metals, especially bidentately bound platinum compounds of the type R2PtIIX2, R2PtIVX2L2, ruthenium complexes of the type [Ru(arene)Lx(PTA)y], or monodentately bound substances of the type [R3PtIIX]Y. |