Publication details
Songbirds avoid the oxidative stress costs of high blood glucose levels: a comparative study.
| Authors | |
|---|---|
| Year of publication | 2024 |
| Type | Article in Periodical |
| Magazine / Source | The Journal of Experimental Biology |
| MU Faculty or unit | |
| Citation | |
| Web | https://pubmed.ncbi.nlm.nih.gov/38054362/ |
| Doi | http://dx.doi.org/10.1242/jeb.246848 |
| Keywords | Antioxidants; Glucose; Hyperglycaemia; Lipid peroxidation; Phylogenetic comparison; Physiological ecology |
| Description | Chronically high blood glucose levels (hyperglycaemia) can compromise healthy ageing and lifespan at the individual level. Elevated oxidative stress can play a central role in hyperglycaemia-induced pathologies. Our findings support the hypothesis that birds evolved adaptations preventing the (glyc)oxidative costs of high blood glucose observed at the within-species level. Such adaptations may explain the decoupled evolution of glycaemia and lifespan in birds and possibly the paradoxical combination of long lifespan and high blood glucose levels relative to mammals. |
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