Publication details
Sledování některých faktorů indikujících možnou autoimunitu (protilátky proti melanocytům, tyreoglobulinu, tyreoidální peroxidáze, parientálním buňkám, mikrosomům) u nemocných vitiligem generalizovaného typu.
| Title in English | Detection of Some Factors Indicating Possible Autoimmunity (Antibodies against Melanocytes, Thyroglobulin, Theroid Peroxidase, Stomach Parietal, Cells, Microsomes) in Patients Suffering from Vitiligo. |
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| Authors | |
| Year of publication | 2001 |
| Type | Article in Periodical |
| Magazine / Source | Česko-slovenská dermatologie |
| MU Faculty or unit | |
| Citation | |
| Field | Dermatovenerology |
| Keywords | vitiligo;autoimmunity;autoantibodies |
| Description | In a group of 43 patients suffering from vitiligo and 15 healthy persons some types of antibody activity with possible relationshi to autoimmunity were measured in serum. In indirect immunofluorescence with homologous melanocytes used as substrate the positivity of reactions was common (up to 72% and 33% in healthy persons respectively) according to the sensitivity of applied method). Antibodies against thyreoid perxidase (+in 27,9%), pariental cells of the stomach (+ in 27,5%), microsomes (+in 27,5%) and thyreoglobuline (+ in 13,9%) were detected. Antinuclear antibodies and antimitochondrial antibodies were not present in atients of examined group. |
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