Publication details
A survey of effects of excessive bromide intake on iodine metabolism in the rat
| Authors | |
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| Year of publication | 2002 |
| Type | Chapter of a book |
| MU Faculty or unit | |
| Citation | |
| Description | We studied the effects of an increased bromide intake, at different levels of iodine supply to the organism, on various aspects of iodine metabolism in the rat. A reduction of the food intake and consequently of the body weight gain was observed in rats drinking water with the highest bromide concentration (5 g bromide per liter). An increase in the relative weight of the thyroids and a significant decrease in the 24-h uptake of radioiodide by the thyroids were also found in these animals, especially in those fed a research low-iodine diet. The concentration ratio [I]/[Br] in the thyroids proved to be a very sensitive marker of even negligibly increased bromide intake in the rats. |
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