Publication details

Differentiation of HL-60 myeloid leukemia cells induced by all-trans retinoic acid is enhanced in combination with caffeic acid

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Authors

VESELSKÁ Renata ZITTERBART Karel AUER Jan NERADIL Jakub

Year of publication 2004
Type Article in Periodical
Magazine / Source International Journal of Molecular Medicine
MU Faculty or unit

Faculty of Medicine

Citation
Field Morphological specializations and cytology
Keywords caffeic acid; all-trans retinoic acid; induced differentiation; HL-60 cells
Description The course of differentiation of HL-60 cells was studied by detecting the occurrence of functionally mature granulocytes and CD-66b expressing cells in ATRA- and/or CA-treated cell populations. Application of CA alone had no or minimal influence on cell differentiation whereas differentiating activity of ATRA was potentiated by CA treatment.
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