Publication details
Toxic effects of cyanobacterial biomass in Japanese quail
| Authors | |
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| Year of publication | 2006 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | Cyanobacteria produce wide range of toxic compounds (cyanotoxins) which became important contaminants of aquatic ecosystems. Although several case studies implicated at least a contribution of toxic cyanobacterial blooms to the mass deaths of different bird species, there is a lack of toxicological experiments focused on avian toxicity of cyanobacteria or cyanotoxins. The aim of this study was to investigate the effects of cyanobacterial biomass using OECD 205: Avian dietary toxicity test with Japanese quail (Coturnix coturnix japonica). Animals were exposed to homogenized cyanobacterial bloom of Microcystis aeruginosa (containing the most prevalent cyanotoxins microcystins) in acute and (sub)chronic study. Effects on biochemical markers related to oxidative stress and detoxication were investigated in different tissues. Exposure to cyanobacterial biomass induced modulations of enzymatic and nonenzymatic antioxidants (including glutathione level and related enzymes) as well as lipid peroxidation. |
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