Publication details
Capillary Electrophoretic Separation and Kinetic Study of Inert Copper(II) Complexes of 1,8-bis(methylphosphonate) Derivative of Cyclam
| Authors | |
|---|---|
| Year of publication | 2006 |
| Type | Article in Periodical |
| Magazine / Source | Polyhedron |
| MU Faculty or unit | |
| Citation | |
| Field | Analytic chemistry |
| Keywords | capillary electrophoresis; kinetics; cyclam-1-8-bis(methylphosphonic acid); copper complexes; isomerization; phosphonate complexes |
| Description | The behaviour of two structural isomers of the copper(II) complex of 1,4,8,11-tetraazacyclotetradecane-1,8-bis(methylphosphonic acid) (H(4)dipon), penta- and hexacoordinated species, was studied by capillary electrophoresis. The separation and determination of both the isomers with the same molecular weight and charge and the free H(4)dipon ligand were achieved in 75 mM disodium tetraborate aqueous solution (pH 9.5) as background electrolyte and, simultaneously, magnitudes of their effective mobilities were determined. The influence of both variables (pH and buffer composition/concentration) on the separation was established and the principle of the separation was proposed. The method of separation was applied to the study of the reaction mechanism of the isomerization. It was proved that the reaction can be explained by several mechanisms with the same fit through experimental data. The first step of the isomerization reaction proceeds relatively slowly and is the rate-determining step of reaction. |