Chondrocytic potential of allogeneous mesenchymal stem cells transplanted without immunosupresion into physeal defects in rabbits.
|Year of publication||2007|
|Type||Article in Periodical|
|Magazine / Source||ACTA VET.|
|MU Faculty or unit|
|Field||Traumatology and orthopaedic surgery|
|Keywords||growth plate injury; bone bridge; limb deformity; physeal repair; rejection|
|Description||Our results demonstrated that hyaline cartilage formation occurs in iatrogenic distal femoral physeal defects treated with allogenic mesenchymal stem cells. Newly formed cartilage in growth plate area became well integrated with the host physis and functional. The continued growth of the rigth femur from its distal physis was apparent. This study is the first report, to our knowledge, of the use of an allogenic mesenchymal stem cells for repair of experimentally damaged physis in rabbits.|