Publication details

Chondrocytic potential of allogeneous mesenchymal stem cells transplanted without immunosupresion into physeal defects in rabbits.


GÁL Petr NEČAS Alois PLÁNKA Ladislav KECOVA Helga KRUPA Petr KŘEN Leoš

Year of publication 2007
Type Article in Periodical
Magazine / Source ACTA VET.
MU Faculty or unit

Faculty of Medicine

Field Traumatology and orthopaedic surgery
Keywords growth plate injury; bone bridge; limb deformity; physeal repair; rejection
Description Our results demonstrated that hyaline cartilage formation occurs in iatrogenic distal femoral physeal defects treated with allogenic mesenchymal stem cells. Newly formed cartilage in growth plate area became well integrated with the host physis and functional. The continued growth of the rigth femur from its distal physis was apparent. This study is the first report, to our knowledge, of the use of an allogenic mesenchymal stem cells for repair of experimentally damaged physis in rabbits.
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