Publication details

Dlouhodobé sledování adolescentů po protinádorové léčbě

Title in English Long term follow-up in adolescents after antitumour therapy
Authors

HRSTKOVÁ Hana BOTHOVÁ Pavla ELBL Lubomír ŠŤASTNÁ Jana

Year of publication 2009
Type Article in Periodical
Magazine / Source Pediatria
MU Faculty or unit

Faculty of Medicine

Citation
Field Paediatry
Keywords Anthracyclines; cardiotoxicity; echocardiohraphz; diastolic function
Description there were evaluated changes of the left ventricle function in 33 asymptomatic patients treated by complex antitumour chemotherapy with anthracyclines for malignancy in childhood (group A) and in 13 patients after finished chemotherapy without antracyclines (group B). The control group (C) included 64 healthy subject. All adolescents were examined using echocardiography. All values were compared between the subgroups. Significant differences in the diastolic left ventricle function were found in patients treated for malignancy in childhood in comparison to healthy population. Significant differences found in the group treated with other drugs (especialy Vinca alcaloids), should be considered for folow-up monitoring.
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