Publication details
Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM.
| Authors | |
|---|---|
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | Nucleic Acids Research |
| MU Faculty or unit | |
| Citation | |
| Field | Physical chemistry and theoretical chemistry |
| Keywords | Kink-turn; RNA flexibility; Molecular Dynamics; Ribosome function |
| Description | We carried out molecular dynamics simulations of the base of the A-site finger from archaeal and three bacterial large subunits. The study showed that despite noticeable differences in the secondary structures, the studied segments adopt almost identical fold and exhibit similar stochastic fluctuations. Geometries of segments from the simulations correspond to structures obtained by Cryo-electron microscopy. |
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