Publication details

Diffuse large B-cell lymphoma in a patient with hyper-IgE syndrome: Successful treatment with risk-adapted rituximab-based immunochemotherapy

Authors

BELADA David SMOLEJ L. STEPANKOVA P. KRALICKOVA P. FREIBERGER Tomáš

Year of publication 2010
Type Article in Periodical
Magazine / Source LEUKEMIA RESEARCH
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords HYPERIMMUNOGLOBULINEMIA-E; HODGKIN LYMPHOMA; JOBS-SYNDROME; MUTATIONS
Description A case of patient with hyper-IgE syndrome and diffuse large B-cell lymphoma who achieved a durable remission after modified immunochemotherapy is rported. Heterozygous point mutation (c.1259A > C) in codon 340 of the DNA-binding domain of STAT3 was detected in the patient .

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