Identification of MicroRNAs associated with early relapse after nephrectomy in renal cell carcinoma patients

• Authors: SLABÝ Ondřej; RÉDOVÁ Martina; POPRACH Alexandr; NEKVINDOVÁ Jana; ILIEV Robert; RADOVÁ Lenka; LAKOMÝ Radek; SVOBODA Marek; VYZULA Rostislav
• Year of publication: 2012
• Type: Article in Periodical
• Magazine / Source: Genes Chromosomes & Cancer
• MU Faculty or unit: Central European Institute of Technology
• Web: http://onlinelibrary.wiley.com/doi/10.1002/gcc.21957/pdf
• Doi: http://dx.doi.org/10.1002/gcc.21957
• Field: Oncology and hematology
• Keywords: microRNA; renal cell carcinoma; relaps; nephrectomy
• Description: Renal cell carcinoma (RCC) is the most common neoplasm of adult kidney. One of the important unmet medical needs in RCC is prognostic biomarker enabling identification of patients at high risk of relapse after nephrectomy. MicroRNAs (miRNAs) constitute a robust regulatory network with posttranscriptional regulatory efficiency for almost one-half of human coding genes, including oncogenes and tumor suppressors.

Related projects

• CEITEC - Central European Institute of Technology