Publication details
Pityriasis rubra pilaris
| Authors | |
|---|---|
| Year of publication | 2012 |
| Type | Article in Proceedings |
| Conference | Konferenční sborník XIX. ročníku Konference mladých lékařů 2012 |
| MU Faculty or unit | |
| Citation | |
| Field | Dermatovenerology |
| Keywords | pityriasis rubra pilaris; erythroderma; palmoplantar keratoderma; follicular hyperkeratosis; retinoids |
| Description | Pityriasis rubra pilaris is a rare chronic papulosquamous skin disorder of unknown etiology. It is characterized by reddish orange scaly plaques, palmoplantar keratoderma, and keratotic follicular papules. The disease may progress to erythroderma with islands of uninvolved skin. Pityriasis rubra pilaris includes both hereditary and acquired forms. Skin resolves in type I usually within 3 years in 80% of patients. The patients suffer from painful paronychias and fissures on palms and soles. The disease is also considerably psychosocially debilitating. The diagnosis is based on clinical and histologic findings. No single therapy is effective, most effective are retinoids, PUVA and methotrexate, nowadays also inhibitors of TNF-alfa. This case report presents a case of 43-years old man, with papulosquamos exanthema, non-responsive to topical treatment, progressing during 2 months in erythroderma. The skin structure began to resolve after 2-weeks therapy of acitretin. Longlasting course of the disease has unfortunately very bad impact to patient's psychosocial life. |