Mgr. Tomáš Loja, Ph.D.

2026

• Creatine kinase B, a downstream effector of c-Myb, controls migration of osteosarcoma cells via regulation of N-cadherin

  POKLUDOVÁ Jana LAPČÍK Petr STANICZKOVÁ ZAMBO Iva KOHOUTEK Jiří ZAPLETALOVÁ Danica MÚDRY Peter ADÁMKOVÁ Dagmar ČERVINKA Jakub LOJA Tomáš LEXA Matej VERNER Jan ŠMARDA Jan BOUCHAL Pavel KNOPFOVÁ Lucia BENEŠ Petr

  Article in Periodical

  Cancer Cell International, year: 2026, volume: 26, edition: 1, DOI

2025

• Functional characterization of 16 variants found in the LDL receptor gene

  KONEČNÁ Kateřina PŘEROVSKÁ Tereza LOJA Tomáš FAJKUSOVÁ Lenka KOUTNÁ Jana KRAMÁREK Michal ALVES Ana Catarina BOURBON Mafalda FREIBERGER Tomáš TICHÝ Lukáš

  Article in Periodical

  JOURNAL OF LIPID RESEARCH, year: 2025, volume: 66, edition: 9, DOI

• Protein structure and interactions elucidated with in-cell NMR for different cell cycle phases and in 3D human tissue models

  RYNEŠ Jan IŠTVÁNKOVÁ Eva KRAFČÍKOVÁ Michaela LUCHINAT Enrico BARBIERI Letizia BANCI Lucia KAMARÝTOVÁ Kristýna LOJA Tomáš FAFÍLEK Bohumil RICO LLANOS Gustavo KREJČÍ Pavel MACUREK Libor TRANTÍRKOVÁ Silvie TRANTÍREK Lukáš

  Article in Periodical

  Communications Biology, year: 2025, volume: 8, edition: 1, DOI

• Regulation of Cell-Nanoparticle Interactions through Mechanobiology

  CASSANI Marco NIRO Francesco FERNANDES Soraia PEREIRA DE SOUSA Daniel MORAZZO Sofia DURIKOVA Helena WANG Tianzheng GONZALEZ-CABALEIRO Lara VRBSKY Jan OLIVER-DE La Cruz Jorge VRANA Šimon PŘIBYL Jan LOJA Tomáš SKLÁDAL Petr CARUSO Frank FORTE Giancarlo

  Article in Periodical

  NANO LETTERS, year: 2025, volume: 25, edition: 7, DOI

2024

• A novel thrombocytopenia-4-causing CYCS gene variant decreases caspase activity: Three-generation study

  ŠTIKA Jiří PEŠOVÁ Michaela STAŇO KOZUBÍK Kateřina SKALNÍKOVÁ Magdalena DOSTÁLOVÁ Lenka LOJA Tomáš RADOVÁ Lenka PALUŠOVÁ Veronika RÉBLOVÁ Kamila VRZALOVÁ Zuzana BLAHÁKOVÁ Ivona TRIZULJAK Jakub ULDRIJAN Stjepan BLATNÝ Jan ŠMÍDA Michal POSPÍŠILOVÁ Šárka DOUBEK Michael

  Article in Periodical

  British journal of haematology, year: 2024, volume: 205, edition: 6, DOI

• Dual Nature of MoO3 Particles in Human-Derived Macrophage Milieu

  NAVRÁTILOVÁ Polina WOJTAS Daniel WÓJCIK Anna ULLATTIL Sanjay Gopal LOJA Tomáš PÁVKOVÁ GOLDBERGOVÁ Monika

  Article in Periodical

  ACS Applied Nano Materials, year: 2024, volume: 7, edition: 18, DOI

• IDENTIFICATION OF CHRONIC MYELOID LEUKEMIA STEM CELLS AT DIAGNOSIS AND EARLY FOLLOW-UP

  ČULEN Martin ROMŽOVÁ Marianna SMITALOVÁ Dagmar LOJA Tomáš BUŠA Daniel VENGLÁŘ Ondřej HERUDKOVÁ Zdeňka BORSKÝ Marek TAUŠ Petr REIGL Tomáš PLEVOVÁ Karla ŠMEJKAL Jiří ŽÁČKOVÁ Daniela STEJSKAL L. RÁČIL Zdeněk MAYER Jiří

  Conference abstract

  Year: 2024, type: Conference abstract

• In-cell NMR suggests that DNA i-motif levels are strongly depleted in living human cells

  VÍŠKOVÁ Pavlína IŠTVÁNKOVÁ Eva RYNEŠ Jan DŽATKO Šimon LOJA Tomáš LENARČIČ ŽIVKOVIC Martina RIGO Riccardo EL-KHOURY Roberto SERRANO-CHACON Israel DAMHA Masad J GONZALEZ Carlos MERGNY Jean-Louis TRANTÍRKOVÁ Silvie TRANTÍREK Lukáš

  Article in Periodical

  Nature Communications, year: 2024, volume: 15, edition: 1, DOI

• Plastic response of macrophages to metal ions and nanoparticles in time mimicking metal implant body environment

  NAVRÁTILOVÁ Polina EMMER Jan TOMÁŠ Tomáš RYBA Luděk BURDA Jan LOJA Tomáš VEVERKOVÁ Jana VÁLKOVÁ Lucie PÁVKOVÁ GOLDBERGOVÁ Monika

  Article in Periodical

  Environmental Science and Pollution Research, year: 2024, volume: 31, edition: 3, DOI

• Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drug

  HOFERKOVÁ Eva ŠEDA Václav CESNÁRIKOVÁ Soňa VERNER Jan LOJA Tomáš MATULOVÁ Květoslava SKUHROVÁ FRANCOVÁ Hana ONDROUŠKOVÁ Eva FILIP Daniel BLAVET Nicolas BOUDNÝ Miroslav MLADONICKÁ PAVLASOVÁ Gabriela VEČEŘA Josef ONDRIŠOVÁ Laura PAVELKOVÁ Petra HLAVÁČ Kryštof KOŠŤÁLOVÁ Lenka MICHAELOU Androniki POSPÍŠILOVÁ Šárka DORAZILOVÁ Jana CHOCHOLA Václav JAROŠ Josef DOUBEK Michael JAROŠOVÁ Marie HAMPL Aleš VOJTOVÁ Lucy KŘEN Leoš MAYER Jiří MRÁZ Marek

  Article in Periodical

  Leukemia, year: 2024, volume: 38, edition: 8, DOI