Project information
Neobvyklé signální dráhy lidských receptorových tyrozinových kináz
- Project Identification
- GA17-09525S
- Project Period
- 1/2017 - 12/2019
- Investor / Pogramme / Project type
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Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Medicine
- Cooperating Organization
-
Institute of Biophysics
Responsible person Assoc. Prof. Mgr. Vítězslav Bryja, Ph.D.
Publications
2018
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Expression of COBLL1 encoding novel ROR1 binding partner is robust predictor of survival in chronic lymphocytic leukemia
haematologica, year: 2018, volume: 103, edition: 2, DOI
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Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome
Cellular Signalling, year: 2018, volume: 2018, edition: 42, DOI
2017
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A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation
Frontiers in Cell and Developmental Biology, year: 2017, volume: 5, edition: MAY, DOI
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ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3
Bone, year: 2017, volume: 105, edition: DEC 2017, DOI
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Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480
Oncotarget, year: 2017, volume: 8, edition: 65, DOI
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One reporter for in-cell activity profiling of majority of protein kinase oncogenes
eLife, year: 2017, volume: 6, edition: "e21536", DOI