Project information
Synthesis and Photochemistry of Isotope Labeled Probes of Neonatal Jaundice Phototherapy

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Project Identification
Project Period
4/2022 - 12/2024
Investor / Pogramme / Project type
Czech Science Foundation
MU Faculty or unit
Faculty of Science

The project aims to prepare novel probes to advance our understanding of chemistry and biology of the clinically important heme degradation product bilirubin during hyperbilirubinemia phototherapy. The pursued approach will combine innovative synthetic chemistry to provide bilirubin, and many of its known degradation products, in isotope-labeled form. In-dept photochemical studies will be used to deliver a detailed mechanistic picture regarding the formation and behavior of the bilirubin fragments generated during phototherapy. Resulting well-characterized probes will be invaluable for biomedical research in the context of hyperbilirubinemia phototherapy.

Sustainable Development Goals

Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.

Sustainable Development Goal No.  3 – Good health and well-being


Total number of publications: 1

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