Project information

New photoactivatable systems for biological studies

Project Identification
ME09021
Project Period
4/2009 - 12/2012
Investor / Pogramme / Project type
Ministry of Education, Youth and Sports of the CR
MU Faculty or unit
Faculty of Science
Keywords
Photochemistry

Photoactivatable compounds (also called caged compounds) are systems which, upon photoactivation, either (1) irreversibly release a species possessing desirable physical, chemical, or biological qualities, while the groups that are responsible for the photoprocess are referred to as photoremovable; or (2) reversibly induce physical or chemical changes in a system; in such cases, they are called photochemical switches and the process is usually photochromic (photochromism is a reversible chemical transformation, induced in one or both directions by the absorption of light, between two forms having different absorption spectra and other photophysical properties). Photoactivatable compounds are of a great interest in connection with biochemical and biological applications (e.g., photoregulations of proteins and enzyme activity, neurotransmitters, ATP, and Ca2+ delivery, or photoactivatable fluorophores), organic synthesis (e.g., photoremovable protecting groups; solid-phase synthesis; microarray fabrica

Publications

Total number of publications: 7


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