Comparison study of Laser Ablation based methods for analysis of kidney stones
|Year of publication
|MU Faculty or unit
|Investigated urinary stones were cut, sealed into resin and the cross-section of the sample was polished and was mapped by laser-ablation based analytical methods. On the base of these measurements, for samples containing whewellit or weddellit (or both of these minerals), the correlation between calcium and carbon distribution was confirmed. The correlation between magnesium and phosphorus can be attributed to the presence of struvite. The correlation between calcium and phosphorus distribution indicates the presence of apatite. The correlation of zinc, sodium or potassium distribution with phosphates was also observed. The aim of next study was to demonstrate the calibration capabilities and limitations of laser ablation based techniques. Calibration pellets were prepared from human urinary calculi with phosphate, oxalate and urate matrix. For this comparative study the most frequently used laser-ablation based analytical techniques were chosen, such as LIBS and LA-ICP-MS. Moreover some unconventional techniques such as simultaneous LIBS-LA-ICP-OES and laser ablation (LA) - LIBS were also utilized.