Febrilní pancytopenie a hepatosplenomegalie jako hlavní symptomy viscerální leishmaniózy.

• Title in English: Febrile pancytopenia and hepatosplenomegaly as leading symptoms of visceral leishmaniasis
• Authors: POLÁK Pavel; SVOBODA Radek; KUBÁČKOVÁ Petra; BRYCHTOVÁ Yvona; PANOVSKÁ Anna; NOHÝNKOVÁ Eva; HUSA Petr; FREIBERGEROVÁ Michaela; PAŘÍZKOVÁ Radana; ŠNELEROVÁ Marta; PÝCHOVÁ Martina; KAMELANDER Jan
• Year of publication: 2012
• Type: Article in Periodical
• Magazine / Source: Vnitřní lékařství
• MU Faculty or unit: Faculty of Medicine
• Field: Epidemiology, infectious diseases and clinical immunology
• Keywords: visceral leishmaniasis; pancytopenia; hepatosplenomegaly; amphothericin B; miltefosin
• Description: The authors present a case report of a patient with febrile pancytopenia, hepatosplenomegaly and weight loss as main symptoms of visceral leishmaniasis. Standard treatment regimen with amphothericin B led to relapse of the disease after several weeks. The definitive curing was reached with cytostatic miltefosin (Impavido©), which is not registered in the Czech Republic. The aim of this article is to point out this imported protozoan infection and its basic clinical and laboratory features.