Publication details

Febrilní pancytopenie a hepatosplenomegalie jako hlavní symptomy viscerální leishmaniózy.

Title in English Febrile pancytopenia and hepatosplenomegaly as leading symptoms of visceral leishmaniasis
Authors

POLÁK Pavel SVOBODA Radek KUBÁČKOVÁ Petra BRYCHTOVÁ Yvona PANOVSKÁ Anna NOHÝNKOVÁ Eva HUSA Petr FREIBERGEROVÁ Michaela PAŘÍZKOVÁ Radana ŠNELEROVÁ Marta PÝCHOVÁ Martina KAMELANDER Jan

Year of publication 2012
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Citation
Field Epidemiology, infectious diseases and clinical immunology
Keywords visceral leishmaniasis; pancytopenia; hepatosplenomegaly; amphothericin B; miltefosin
Description The authors present a case report of a patient with febrile pancytopenia, hepatosplenomegaly and weight loss as main symptoms of visceral leishmaniasis. Standard treatment regimen with amphothericin B led to relapse of the disease after several weeks. The definitive curing was reached with cytostatic miltefosin (Impavido©), which is not registered in the Czech Republic. The aim of this article is to point out this imported protozoan infection and its basic clinical and laboratory features.