Publication details

Diabetes 1. typu a LADA – výskyt HLA DRB1*03 a DRB1*04 alel u dvou věkově odlišných skupin diabetiků.

Title in English Diabetes type 1 (T1D) and LADA - occurrence of HLA-DRB1 * 03 and DRB1 * 04 alleles in two different age groups of diabetics.
Authors

WEBER Pavel MELUZÍNOVÁ Hana NEVRLÁ Jana MATĚJOVSKÁ KUBEŠOVÁ Hana POLCAROVÁ Vlasta ČEJKOVÁ Pavla ČERNÁ Marie

Year of publication 2009
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description Diabetes mellitus type 1 (DM1) with the emergence in adulthood and latent autoimmune diabetes in adults (LADA) are both associated with autoimmune insulitidou and specific high-risk HLA genotype II. classes. The aim of the study was to analyze the clinical characteristics of time and the emergence of DM after 35 years of age. In particular, define the role of the possible role of elderly in the development of this type of DM and to compare these characteristics with time of diabetics in middle age (including an analysis of HLA-DRB1 genotype).

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