Publication details

Pohlaví a drogová závislost: od animálních modelů ke klinické praxi

Title in English Gender and drug addiction: from the animal models to human medicine
Authors

AMCHOVÁ Petra KUČEROVÁ Jana

Year of publication 2015
Type Article in Periodical
Magazine / Source Česká a slovenská psychiatrie
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords animal models; drug addiction; gender differences; pharmacodynamics; pharmacokinetics; sex hormones; genes; socio-cultural differences
Description Drug addiction is a serious medical and psychosocial problem which leads to organic harm of the body as well as distortion of the normal functioning of affected persons within the society and family. There is a large body of clinical evidence suggesting differential characteristics of the disorder in men and women. Despite the absolute number of female drug abusers is lower than the male ones, women usually show higher escalation rate, more frequent relapses and more difficulties when discontinuing the drug use. These gender specific differences will require specific treatment strategies for men and women in the near future.
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