Publication details

Multimodální farmakologické působení trazodonu

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Title in English Multimodal pharmacological actions of trazodone
Authors

ŠULCOVÁ Alexandra

Year of publication 2015
Type Article in Periodical
Magazine / Source Psychiatrie
MU Faculty or unit

Central European Institute of Technology

Citation
Web http://www.tigis.cz/images/stories/psychiatrie/2015/01/09_sulcova_psych_1-15.pdf
Field Psychiatry, sexuology
Keywords trazodone ; multimodal mechanisms ; efficacy ; dosage forms
Description Trazodone was primarily classified as tetracyclic antidepressant, later known as a member of the subgroup SARI (Serotonin2 Antagonists/Reuptake Inhibitors), according to the main confirmed pharmacological mechanisms of action, which correspond beside antidepressant also to anxiolytic and hypnotic effects. A successive investigation of multimodal trazodone affinities and activities at neuronal binding sites is extending the view on its therapeutic potential. This article summarizes that currently available information.
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