Publication details

Gluten ataxia is better classified as non-celiac gluten sensitivity than as celiac disease: a comparative clinical study

Authors

RODRIGO Luis HERNÁNDEZ LAHOZ Carlos LAURET Eugenia RODRIGUEZ PELÁEZ Maria SOUČEK Miroslav CICCOCIOPPO Rachele KRUŽLIAK Peter

Year of publication 2016
Type Article in Periodical
Magazine / Source Immunologic Research
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.1007/s12026-015-8750-1
Field Other specializations of internal medicine
Keywords Gluten ataxia; Non-celiac gluten sensitivity; Celiac disease; Comparative study
Description Gluten ataxia (GA) has customarily been considered to be the main neurological manifestation of celiac disease (CD). In recent years, the condition of non-celiac gluten sensitivity (NCGS) has been defined, which includes some patients who are not considered ‘‘true celiacs.’’ We performed a comparative clinicopathological study of these three entities. We studied 31 GA, 48 CD and 37 NCGS patients, prospectively in the same center for a period of 7 years. The protocol study included two serological determinations for gluten sensitivity [anti-gliadin IgA and IgG (AGA) and anti-tissue transglutaminase IgA (TG) antibodies], HLA-DQ2 typing, and duodenal histological assessment. Demographics and investigative findings were compared.

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