Biomacromolecular structure quality – improvement or stagnation?
|Year of publication||2017|
|Type||Appeared in Conference without Proceedings|
|MU Faculty or unit|
|Description||We have performed wide scale analysis of trends in quality and size of biomacromolecules and their ligands. 70 diverse factors have been considered. Information about structures and their quality have been obtained from the Protein Data Bank, while the state of ligand quality has been sourced by our database ValidatorDB. Existence of some discovered trends was expected (e.g., newer structures have better quality). Other trends surprised us (e.g., ligand quality is stagnant at best, currently utilised structure validation methods do not validate ligands well). Discovered trends are openly available in the ValTrendsDB database.|