Publication details

ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data

Authors

BYSTRÝ Vojtěch REIGL Tomáš KREJČÍ Adam DEMKO Martin HANÁKOVÁ Barbora GRIONI Andrea KNECHT Henrik SCHLITT Max DREGER Peter SELLNER Leopold HERRMANN Dietrich PINGEON Marine BOUDJOGHRA Myriam RIJNTJES Jos POTT Christiane LANGERAK Anton W. GROENEN Patricia J. T. A. DAVI Frederic BRUGGEMANN Monika DARZENTAS Nikos

Type Article in Periodical
Magazine / Source Bioinformatics
MU Faculty or unit

Central European Institute of Technology

Citation
WWW https://academic.oup.com/bioinformatics/article-abstract/33/3/435/2580414/ARResT-Interrogate-an-interactive-immunoprofiler?redirectedFrom=fulltext
Doi http://dx.doi.org/10.1093/bioinformatics/btw634
Field Biochemistry
Keywords REPERTOIRE
Description Motivation: The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task. Results: We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of immunogenetic data by numerous criteria, calculate several relevant statistics, and present results in the form of multiple interconnected visualizations.
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