Publication details

Studie RELAX-AHF2:RELAXin in Acute Heart Failure-2

Title in English The RELAX-AHF2 Trial:RELAXin in Acute Heart Failure-2
Authors

ŠPINAROVÁ Lenka ŠPINAR Jindřich

Year of publication 2018
Type Article in Periodical
Magazine / Source Intervenční a akutní kardiologie
MU Faculty or unit

Faculty of Medicine

Citation
Keywords acute heart failure, serelaxin,cardiovascular mortality, overall mortality, safety
Description Serelaxin is a recombinant form of human relaxin-2 with favourable haemodynamic properties.The RELAX AHF trial tested this substance in patients with acute heart failure. There was no improvement in 5 days hospitalisation and no reduction in 180 days cardiovascular mortality. There was no difference in all-cause mortality. The study was well tolerated with adverse effects comparable to placebo.

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